K+-Dependent Composite Gating of the Yeast K+ Channel, Tok1
نویسندگان
چکیده
منابع مشابه
Mutations in the pore regions of the yeast K+ channel YKC1 affect gating by extracellular K+.
The product of the Saccharomyces cerevisiae K+-channel gene YKC1 includes two pore-loop sequences that are thought to form the hydrophilic lining of the pore. Gating of the channel is promoted by membrane depolarization and is regulated by extracellular K+ concentration ([K+]o) both in the yeast and when expressed in Xenopus oocytes. Analysis of the wild-type current now shows that: (i) [K+]o s...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1999
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(99)77137-7